I should return to Cerrigar and speak with Bryona. She may have uncovered a means to purge Astaroth's blood once and for all.
Phase2
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Speak with Bryona
Phase8
Phase8Description
The blood relic I recovered was but one of several, each a vessel of Astaroth's power hidden across Sanctuary. As long as these relics remain, so does Astaroth.
Bryona believes the Horadrim sealed these relics within Strongrooms - protected chambers buried deep within Nightmare Dungeons. I need to use a Nightmare Sigil to access these chambers.
Phase96
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Use a Nightmare Sigil to find a Strongroom
Phase103
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Retrieve a {ITEM:S09_QST_Main_DGN_AstarothBloodItem} from a Strongroom
Phase54
Phase54Description
With the blood relic I recovered from the Horadric Strongroom, I should return to Bryona in Cerrigar. Once contained within the Horadric Wayfinder, the relic's influence will be sealed.
Each fragment secured brings us one step closer to preventing Astaroth's full resurgence.